Lactose intolerance. The inflammation in the lining of your intestine can keep you from producing the enzyme needed to break down lactose, which is the sugar in dairy products. Undigested lactose can cause gas and diarrhea. Irritability and depression. Children with celiac disease are extremely irritable. In adults, celiac disease can cause symptoms of depression , lack of energy, and problems with memory and concentration. Research shows that these symptoms may be due to malabsorption of vitamin B6 and tryptophan.
These are important nutrients you need to produce chemicals called " neurotransmitters " that stimulate nerve cells in your brain. Lymphoma and bowel cancer.
If celiac disease is left untreated, it can increase your risk for developing certain types of digestive system cancers. Lymphoma of the small intestine is a rare type of cancer but may be 30 times more common in people with celiac disease.
Adenocarcinoma of the intestine and cancer of the esophagus are also more common. This increased risk of cancer is probably due to the irritation and inflammation in untreated celiac disease over a long period of time. Low birth-weight babies. These are only five of the most common celiac disease complications related to the gastrointestinal tract. Read more about gastrointestinal complications.
If not treated early enough, celiac disease continues to cause inflammation and gradually destroys your digestive system, particularly the small intestine. This causes your small bowel to absorb nutrients less effectively, leading to a condition called malnutrition. This is characterized by a severe lack of vitamins, minerals, and other nutrients in the body. Individuals who are malnourished usually have deficiencies in key nutrients such as iodine, vitamin A, zinc, and iron. Because of critical nutritional deficiency, your brain may not work properly, and your body is unable to fight off infections, recover from injury, and maintain other biological processes.
For celiac patients with serious malnutrition, muscles may start to degenerate and they find it challenging to keep warm. Generally, they feel confused, weary, dizzy, irritable, unable to concentrate, and severely fatigued. Wounds may take an unusually long time to heal, and the thyroid gland may start to swell goiter.
Severe malnutrition may also cause anxiety, depression, drastic weight loss, potbelly, dry skin and hair, and sunken eyes. In children with celiac disease, malnutrition may cause delayed development and stunted or poor growth. However, keep in mind that celiac disease is not the only known cause of malnutrition. DH is characterized by a burning, blistering, and itchy rash that may affect the quality of your life.
Both the itching and rash occur on the back, scalp, buttocks, knees, and elbows. In fact, between 15 and 25 percent of celiac patients experience this itchy skin rash, according to the NIH. The rash and itchiness results from the reaction of immune system antibodies called immunoglobulin A IgA and gluten proteins, especially gliadin.
Read more about celiac disease and DH. Lactose intolerance is a condition where the person is unable to digest, absorb or tolerate lactose, a simple type of natural sugar most commonly found in dairy. As such, lactose-intolerant people are recommended not to consume yogurt, milk, and other dairy products. A person becomes lactose intolerant when their small intestine is unable to make an adequate amount of lactase, an enzyme that is responsible for digesting and breaking down lactose.
Undigested lactose will eventually move to the colon where it interacts with gut bacteria in the large intestine. This leads to digestive issues like diarrhea, excess gas, bloating, nausea, and abdominal discomfort.
The inflammatory reaction to gluten not only destroys villi but also damages cells that produce lactase, rendering your small intestines unable to produce enough enzymes to break down lactose. In medical terms, infertility is defined as the inability to develop pregnancy after 1 year of trying without protection. There are two kinds.
Some medical researchers and clinicians now believe that untreated celiac disease may be responsible for certain unexplained cases of infertility in both men and women.
In a study published in the journal Arquivos de Gastroenterologia , scientists discovered that the prevalence of otherwise unexplained infertility in women with celiac disease was significant at around 4 percent.
This seems to concur with another Danish study published in Human Reproduction. After analyzing medical records of 6, celiac women and comparing with those of 63, non-celiac women, researchers concluded that untreated celiac disease may increase the risk of infertility and pregnancy complications like miscarriage and stillbirths.
More in-depth research is needed to look into the long-term effects of celiac disease on men. Nonetheless, an earlier Italian study noticed that men with celiac diseases may have an increased risk of infertility than the general population.
Individuals with undiagnosed or untreated celiac disease may suffer from the following mineral and vitamin deficiencies:. When the small intestine is damaged, it cannot absorb enough iron, leading to iron-deficiency anemia.
Vitamin A deficiency: Severe lack of vitamin A may increase risk of infection, as well as cause night blindness, loss of vision, and dry eyes. Zinc deficiency : Zinc is needed for a strong immune system and proper functioning of enzymes.
Its deficiency leads to diarrhea, hair loss, appetite loss, wounds that take long to heal, stunted growth, and more. Vitamin B deficiency : This vitamin is crucial for production of red blood cells.
Its deficiency will likely cause difficulty concentrating, chronic fatigue, and nerve issues. Niacin deficiency : This may lead to pellagra, a condition that is typified by dementia, dermatitis, and diarrhea. Other deficiencies that have been linked to undiagnosed celiac disease include folate, calcium, riboflavin, vitamin D, magnesium, and fiber. Although once thought to be a disorder restricted to children, research has shown that celiac disease is a fairly common disease affecting about one percent of the US population.
In children, the symptoms are most commonly related to the digestive system and may include bloating, vomiting, constipation, gas, and diarrhea. It may also cause stunted growth, delayed puberty, and slowed development. In adults, however, the gastrointestinal symptoms may be less common, and signs of the condition are likely associated with prolonged malabsorption. These long-term effects are usually manifested as celiac disease complications, including:.
Constipation, one of the most obvious complications from a damaged GI. Although it is one of the first symptoms, undiagnosed celiac disease can result in chronic constipation.
Chronic diarrhea is another gastrointestinal complication linked to untreated celiac disease. It manifests as an oily, frothy and watery stool that persists more than 4 weeks.
Irritable bowel disease is one of the most common celiac disease complications. Chronic pancreatitis is caused by an inflamed pancreas, making it unable to produce digestive enzymes and juices. Celiac disease may also cause blockage of the pancreatic duct, a tube that carries digestive juices to the stomach. As celiac disease damages your small intestine, serious and prolonged inflammation may cause severe malabsorption of nutrients.
This, in turn, causes critical nutritional deficiency and malnutrition. This makes the patient weary, fatigued, dizzy, unable to think clearly, and confused.
It may also cause delayed wound recovery. Nutritional deficiency can also cause a dangerous lack of vitamins such as vitamin A, vitamin B12, vitamin D, niacin, and riboflavin, all of which are needed for the proper functioning of the immune system and other biological processes. Malabsorption may also lead to a severe lack of minerals like iron, folate, calcium, zinc, magnesium, and much more. This causes osteoporosis, iron-deficiency anemia, and osteopenia, just to mention a few.
As celiac disease damages the small intestine, it also renders it unable to produce enough lactase enzyme. It is estimated to affect 1 in people worldwide.
Two and one-half million Americans are undiagnosed and are at risk for long-term health complications. When people with celiac disease eat gluten a protein found in wheat, rye and barley , their body mounts an immune response that attacks the small intestine. These attacks lead to damage on the villi, small fingerlike projections that line the small intestine, that promote nutrient absorption. When the villi get damaged, nutrients cannot be absorbed properly into the body. Celiac disease is hereditary, meaning that it runs in families.
People with a first-degree relative with celiac disease parent, child, sibling have a 1 in 10 risk of developing celiac disease. Celiac disease can develop at any age after people start eating foods or medicines that contain gluten. Left untreated, celiac disease can lead to additional serious health problems.
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