In those who are poorly compliant with or intolerant of the potassium citrate, dietary citrate may be an addition, or even an alternative, to potassium citrate therapy.
While citrus fruits and juices contain some citrate, they generally do not contain enough to reduce stone recurrence. Studies investigating the effects of citrus juices have used amounts ranging from millilitres ml to 1. Drinking excessive amounts of fruit juice contribute to a higher carbohydrate load and can lead to weight gain due to a higher energy intake, both of which may increase kidney stone risk.
An easy to use, well tolerated and cost effective solution is to use a mixture of ml reconstituted lemon or lime juice with 2 L of water. Impairment of citrate metabolism can lead to accumulation of citrate and calcium-citrate complex, hypocalcaenemia, hypomagnesaemia, and metabolic acidosis.
The risk of hypocalcaenemia and hypomagnesaemia is low, because citrate is metabolized in a the kidneys , the liver , and skeletal muscle , and calcium and magnesium are subsequently released back into the circulation. Calcium sensing receptor CaSR in tubular system regulates citrate transport via dicarboxylate transporter NaDC1 from tubular fluid.
Many bacteria produce siderophore molecules, with citrate at their core, to pick iron from their environment. Citrate binds iron ions, and albumin binds both iron ions and citrate. Ferric citrate supplementation is used to increase iron stores and haemoglobin , and it decreases serum phosphate levels, and is therefore used in treatment of dialysis and CKD patients.
In the brain tumours, 52 Fe uptake administered as citrate reflects the status of the BBB , and not the number of transferrin receptors Roelcke et al. Uptake into normal brain is low but measurable Calonder et al. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy.
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Updated visitor guidelines. You are here Home » citric acid, potassium citrate, and sodium citrate. Top of the page. What is the most important information I should know about citric acid, potassium citrate, and sodium citrate? What is citric acid, potassium citrate, and sodium citrate? Citric acid and sodium citrate are alkalinizing agents that make the urine less acidic. What should I discuss with my healthcare provider before taking citric acid, potassium citrate, and sodium citrate?
You should not use this medication if you are allergic to it, or if you have:. How should I take citric acid, potassium citrate, and sodium citrate? You may chill the mixed medicine to make it taste better, but do not allow it to freeze.
What happens if I miss a dose? What happens if I overdose? Seek emergency medical attention if you think you have used too much of this medicine. What should I avoid while taking citric acid, potassium citrate, and sodium citrate? Avoid eating foods that are high in salt, or using extra table salt on your meals. What are the possible side effects of citric acid, potassium citrate, and sodium citrate?
Call your doctor at once if you have any of these serious side effects:. What other drugs will affect citric acid, potassium citrate, and sodium citrate? Where can I get more information? Copyright Cerner Multum, Inc.
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